Chordoma Foundation

New chordoma cell lines available to the research community

This month brought two exciting milestones in our ongoing quest to supply the research community with the scientific materials needed to develop new treatments for chordoma.

Five new cell lines created at University of Ulm

First, we are thrilled to announce that we have validated five new chordoma cell lines, representing primary, recurrent, and metastatic tumors. Created by Drs. Kevin Mellert and Peter Möller at the University of Ulm in Ulm, Germany, these new lines bring the total number of validated chordoma cell lines to 17.

These new lines will provide researchers with a more diverse set of disease models in which to study chordoma biology and test new drugs, helping to ensure that findings are applicable to the entire chordoma patient community. They are currently in the process of being expanded and banked, and will soon be available through our Cell Line Repository.

The University of Ulm has proved to be remarkably capable in the art of cell culture, developing 9 of the 17 validated cell lines in our repository. In recognition of their significant, and most recent, contributions to the field, the Chordoma Foundation is proud to award prizes totaling $50,000 to Dr. Möller and Dr. Mellert — $10,000 for each cell line.

MUG-CC1 line now available to researchers

Until recently, only eight of the validated cell lines were publicly available to researchers. This month, we are delighted to report that a ninth cell line — a clival chordoma line called MUG-CC1, created by Dr. Beate Rinner of the Medical University of Graz in Austria — is now available through our Cell Line Repository.

Validated in September 2015, this new line has completed the expansion and banking process and is now available to researchers and companies worldwide through our partnership with the American Type Culture Collection (ATCC) — the largest and most reputable public cell line repository. Mug-CC1 is the second validated clival cell line in our repository providing additional diversity to our cell line collection.

For questions about how to access chordoma cell lines or submit a line to the Cell Line Repository, please contact our Manager of Research Patty Cogswell at pattycogswell@chordomafoundation.org.

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