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U-CH17M

General Characteristics

Age:38 years
Gender:Male
Disease Origin:Sacral
Disease Status:Metastatic
Metastatic Site(s):Skin, Soft tissue
Sample Origin:Soft tissue
Source:Kevin Mellert, Peter Moller
University of Ulm

Molecular Features

Cell morphology:Physaliferous
T expression:Positive; 11.7x that of U-CH2
T localization:Nuclear
CD24 expression:Positive; 6.1x that of U-CH2
HLA Type:
Chromosomal abnormalities:Uncharacterized
Sequence data:WGS and Transcriptome data available contact researchteam@chordoma.org
Validation results:Validation Report

Growth Conditions

Growth medium:IMDM: RPMI-1640 (4:1) +10% FBS
Freeze medium:70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO
Culture conditions:Temperature: 37°C
Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Subculturing instructions:Cell Culture Procedures

Publications

Characterized By:
  • Jäger D, Lechel A, Tharehalli U, Seeling C, Möller P, Barth TFE, Mellert K. (2017) U-CH17P, -M and -S, a new cell culture system for tumor diversity and progression in chordoma. Int J Cancer doi: 10.1002/ijc.31161.