General Characteristics
Age: <20 years
Gender: Male
Disease Origin: Clival
Disease Status: Recurrent, Metastatic
Metastatic Site(s): Lung, Scalp, Chest wall
Sample Origin: Scalp
Prior Radiation: N/A
Prior Systemic Therapy: N/A
Source: Kevin Mellert, Peter Moller, University of Ulm
Notes: This cell line was derived from the CF365 PDX model
Molecular Features
Cell Morphology: Physaliferous
TBXT Expression: Positive; 3x that of U-CH1
TBXT Localization: Nuclear
CD24 Expression:
HLA Type:
Sequence Data: WES and transcriptome data available: raw sequencing data in Cavatica (Chordoma Foundation Dataset) and summary data in PedcBioportal. Contact researchteam@chordoma.org with any questions.
SMARCB1 Status: SMARCB1 deletion
Validation Results: Validation Report
Growth Conditions
Growth Medium: (4:1) IMDM/RPMI 1640 + 10% FBS + 1% NEAA + 1% GlutaMAX
Freeze Medium: 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO
Culture Conditions: Temperature: 37°C
Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Subculturing Instructions: Cell Culture Procedures
Publications
Characterized By:
- Not yet published