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U-CHCF365

General Characteristics

Age: <20 years
Gender: Male
Disease Origin: Clival
Disease Status: Recurrent, Metastatic
Metastatic Site(s): Lung, Scalp, Chest wall
Sample Origin: Scalp
Prior Radiation: N/A
Prior Systemic Therapy: N/A
Source: Kevin Mellert, Peter Moller
University of Ulm
Notes: This cell line was derived from the CF365 PDX model

Molecular Features

Cell Morphology: Physaliferous
TBXT Expression: Positive; 3x that of U-CH1
TBXT Localization: Nuclear
CD24 Expression:
HLA Type:
Sequence Data:

WES and transcriptome data available: raw sequencing data in Cavatica (Chordoma Foundation Dataset) and summary data in PedcBioportal. Contact researchteam@chordoma.org with any questions.

SMARCB1 Status: No expression
Validation Results: Validation Report

Growth Conditions

Growth Medium: IMDM : RPMI-1640 (4:1) + 10% FCS, L-glutamnine
Freeze Medium: 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO
Culture Conditions: Temperature: 37°C
Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Subculturing Instructions: Cell Culture Procedures

Publications

Characterized By:
  • Not yet published