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General Characteristics

Age:<20 years
Disease Origin:Clival
Disease Status:Recurrent, Metastatic
Metastatic Site(s):Neck, Parotid
Sample Origin:Clivus
Source:Chordoma Foundation/START
Notes:This PDX model is part of a progression model from the same patient; CF555 was derived from a local recurrence of a clival chordoma. Other PDX models in this longitudinal series include CF459 and CF539. Timeline of tumor samples is: CF459 => CF539 => CF555. This PDX model was developed from the same tumor sample as the UM-Chor5C cell line.

Molecular Features

T localization:Nuclear
P16 expression:In Progress
SMARCB1 expression:Yes
Prior radiation:Yes
Prior systemic therapy:Yes
Chromosomal abnormalities:In Progress
Sequence data:In Progress

Growth Characteristics

Model animal strain:NSG


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