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U-CH17P

General Characteristics

Age: 38 years
Gender: Male
Disease Origin: Sacral
Disease Status: Metastatic
Prior Radiation: No
Prior Systemic Therapy: No
Source: Kevin Mellert, Peter Moller
University of Ulm

Molecular Features

Cell Morphology: Physaliferous
TBXT Expression: Positive; 9x that of U-CH2
TBXT Localization: Nuclear
CD24 Expression: Positive; 8x that of U-CH2
HLA Type:
Sequence Data:

WGS and transcriptome data available: raw sequencing data in Cavatica (Chordoma Foundation Dataset) and summary data in PedcBioportal. Contact researchteam@chordoma.org with any questions.

SMARCB1 Status:
Validation Results: Validation Report

Growth Conditions

Growth Medium: IMDM: RPMI-1640 (4:1) +10% FBS
Freeze Medium: 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO
Culture Conditions: Temperature: 37°C
Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Subculturing Instructions: Cell Culture Procedures

Publications

Characterized By:
  • Jäger D, Lechel A, Tharehalli U, Seeling C, Möller P, Barth TFE, Mellert K. (2017) U-CH17P, -M and -S, a new cell culture system for tumor diversity and progression in chordoma. Int J Cancer doi: 10.1002/ijc.31161.