General Characteristics
| Age: | <20 years |
| Gender: | Male |
| Disease Origin: | Clival |
| Disease Status: | Primary |
| Source: | Dr. Mark Prince and John Henry Owen University of Michigan |
| Notes: | This cell line was developed from the same tumor as the CF459 PDX model. The UM-Chor5 series is a progression model from the same patient; UM-Chor5 is derived from the primary clival tumor at initial diagnosis. |
Molecular Features
| Cell morphology: | Physaliferous |
| T expression: | Positive; 1.9x that of U-CH2 |
| T localization: | Nuclear |
| CD24 expression: | Positive; 1.5x that of U-CH2 |
| SMARCB1 expression: | No |
| HLA Type: | |
| Chromosomal abnormalities: | Uncharacterized |
| Sequence data: | |
| Validation results: | Validation Report |
Growth Conditions
| Growth medium: | IMDM: RPMI-1640 (4:1) +10% FBS |
| Freeze medium: | 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO |
| Culture conditions: | Temperature: 37°C Atmosphere: air, 95%; carbon dioxide (CO2), 5% |
| Subculturing instructions: | Cell Culture Procedures |
Publications
Characterized By:
|