General Characteristics
| Age: | <20 years |
| Gender: | Male |
| Disease Origin: | Clival |
| Disease Status: | Recurrent, Metastatic |
| Metastatic Site(s): | Neck, Parotid |
| Sample Origin: | Neck (subcutaneous) |
| Source: | Chordoma Foundation/START |
| Notes: | This PDX model is part of a progression model from the same patient; CF538 was derived from a metastatic recurrence (from the neck) of a clival chordoma. Other PDX models in this longitudinal series include CF459 (primary tumor), CF539 (parotid metastasis) and CF555 (local recurrence). Timeline of tumor samples is: CF459 => CF538, CF539 => CF555. |
Molecular Features
| Histology: | |
| T localization: | Nuclear |
| P16 expression: | No |
| SMARCB1 expression: | No |
| Prior radiation: | |
| Prior systemic therapy: | |
| Chromosomal abnormalities: | In Progress |
| Sequence data: | In Progress |
Growth Characteristics
| Model animal strain: | Nude |
Publications
- Not yet published