General Characteristics
| Age: | <20 years |
| Gender: | Male |
| Disease Origin: | Clival |
| Disease Status: | Primary |
| Source: | Chordoma Foundation/START |
| Notes: | This PDX model is part of a progression model from the same patient; CF459 was derived from the primary clival chordoma. Other PDX models in this longitudinal series include CF538 (recurrent neck metastasis), CF539 (recurrent parotid metastasis) and CF555 (local recurrence). Timeline of tumor samples is: CF459 => CF538, CF539 => CF555. |
Molecular Features
| Histology: | |
| T localization: | Nuclear |
| P16 expression: | Yes |
| SMARCB1 expression: | In Progress |
| Prior radiation: | No |
| Prior systemic therapy: | No |
| Chromosomal abnormalities: | In Progress |
| Sequence data: | In Progress |
Growth Characteristics
| Model animal strain: | Nude |
Publications
- Not yet published