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General Characteristics

Age:61 years
Disease Origin:Sacral
Disease Status:Primary
Source:Sagar Shah and Alfredo Quiñones-Hinojosa
Johns Hopkins University

Molecular Features

Cell morphology:Physaliferous
T expression:Positive; 9.2x that of U-CH2 and with T amplification
T localization:Nuclear
CD24 expression:Positive; 6.4x that of U-CH2
HLA Type:A24
Chromosomal abnormalities:Multiple, including amplification of T/brachyury
Sequence data:WGS and Transcriptome data available contact
Validation results:Validation Reports

Growth Conditions

Growth medium:DMEM/F12+10%FBS+glutamine
Freeze medium:70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO
Culture conditions:Temperature: 37°C
Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Subculturing instructions:Cell Culture Procedures


Characterized By:
  • Hsu W, Mohyeldin A, Shah SR, ap Rhys CM, Johnson LF et al. (2011) Generation of chordoma celll line JHC7 and the identification of Brachyury as a novel molecular target. J Neurosurg 115(4): 760-9. PubMed: 21699479.