CF539

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  3. CF539

General Characteristics

Age: <20 years

Gender: Male

Disease origin: Clival

Disease status: Recurrent, Metastatic

Metastatic site(s): Neck, Parotid

Prior radiation: N/A

Prior systemic therapy: N/A

Source: Chordoma Foundation

Notes: This PDX model is part of a progression model from the same patient; CF539 was derived from a metastatic recurrence (in the parotid) of a clival chordoma. Other PDX models in this longitudinal series include CF459, CF538 and CF539. Timeline of tumor samples is: CF459 => CF538, CF539 => CF555.

Molecular Features

Histological subtype: Conventional

Histology features: TBXT, H&E

Sequence data: PedcBioPortal

SMARCB1 status: truncating mutation Lys16*

Notable genomic alterations:

Growth Characteristics

Model animal strain: Nude

Publications

  • Not yet published