General Characteristics
| Age: | 78 |
| Gender: | Female |
| Disease Origin: | Sacral |
| Disease Status: | Recurrent + Metastatic |
| Metastatic Site(s): | Thigh, sacrum, ilium, clavicle, lungs, peritoneum, lymph nodes, adrenal gland, and thyroid |
| Sample Origin: | Pleural effusion |
| Prior Radiation: | Yes |
| Prior Systemic Therapy: | Yes (imatinib, olaparib) |
| Source: | Kevin Mellert University of Ulm |
| Notes: | This cell line was developed from cells isolated from pleural effusion fluid. |
Molecular Features
| Cell Morphology: | Mostly non-physaliferous |
| TBXT Expression: | Positive |
| TBXT Localization: | Nuclear |
| CD24 Expression: | |
| HLA Type: | |
| Sequence Data: | |
| SMARCB1 Status: | Presumed SMARCB1-null (poorly differentiated) |
| Validation Results: | Validation Report |
Growth Conditions
| Growth Medium: | 400ml IMDM, 100ml RPMI 1640, 50ml FCS, 6ml Pen/Strep, 6ml L-Glutamin |
| Freeze Medium: | 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO |
| Culture Conditions: | Temperature: 37°C Atmosphere: air, 95%; carbon dioxide (CO2), 5% |
| Subculturing Instructions: | Cell Culture Procedures |
Publications
Characterized By:
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