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General Characteristics

Age:<20 years
Disease Origin:Clival
Disease Status:Recurrent, Metastatic
Metastatic Site(s):Neck, Parotid
Sample Origin:Parotid
Source:Chordoma Foundation/START
Notes:This PDX model is part of a progression model from the same patient; CF539 was derived from a metastatic recurrence (in the parotid) of a clival chordoma. Other PDX models in this longitudinal series include CF459, CF538 and CF539. Timeline of tumor samples is: CF459 => CF538, CF539 => CF555.

Molecular Features

T localization:Nuclear
P16 expression:Yes
SMARCB1 expression:Yes
Prior radiation:
Prior systemic therapy:
Chromosomal abnormalities:In Progress
Sequence data:In Progress

Growth Characteristics

Model animal strain:Nude


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