General Characteristics
Age: 59 years
Gender: Male
Disease origin: Clival
Disease status: Recurrent
Prior radiation: Yes
Prior systemic therapy: No
Source: Byron Hann, Joanna Phillips, University of California, San Francisco (UCSF)
Molecular Features
Histological subtype: Conventional
Sequence data: PedcBioPortal
SMARCB1 status: Structural variant (likely inactivating; low mRNA expression)
Notable genomic alterations:
Growth Characteristics
Model animal strain: Nude
Publications
Generation of a patient-derived chordoma xenograft and characterization of the phosphoproteome in a recurrent chordoma. Davies JM, Robinson AE, Cowdrey C, Mummaneni PV, Ducker GS, Shokat KM, Bollen A, Hann B, Phillips JJ. J Neurosurg. 2014 Feb;120(2):331-6. doi: 10.3171/2013.10.JNS13598.