General Characteristics
Age: 61 years
Gender: Female
Disease origin: Clival
Disease status: Primary
Prior radiation: No
Prior systemic therapy: No
Source: Byron Hann, Joanna Phillips, University of California, San Francisco (UCSF)
Molecular Features
Histological subtype: Conventional
Histology features: TBXT (link) + H&E (link)
Sequence data: PedcBioPortal
SMARCB1 status: Truncating mutation Gln182*
Notable genomic alterations:
Growth Characteristics
Model animal strain: NSG
Publications
Generation of a patient-derived chordoma xenograft and characterization of the phosphoproteome in a recurrent chordoma. Davies JM, Robinson AE, Cowdrey C, Mummaneni PV, Ducker GS, Shokat KM, Bollen A, Hann B, Phillips JJ. J Neurosurg. 2014 Feb;120(2):331-6. doi: 10.3171/2013.10.JNS13598.