Chordoma Foundation


General Characteristics

Age: <20 years
Gender: Male
Disease Origin: Clival
Disease Status: Primary
Source: Dr. Mark Prince and John Henry Owen
University of Michigan
Notes: This cell line was developed from the same tumor as the CF459 PDX model.  The UM-Chor5 series is a progression model from the same patient; UM-Chor5 is derived from the primary clival tumor at initial diagnosis.


Molecular Features

Cell morphology: Physaliferous
T expression: Positive; 1.9x that of U-CH2
T localization: Nuclear
CD24 expression: Positive; 1.5x that of U-CH2
SMARCB1 expression: No
HLA Type:
Chromosomal abnormalities: Uncharacterized
Sequence data:
Validation results: Validation Report


Growth Conditions

Growth medium: IMDM: RPMI-1640 (4:1) +10% FBS
Freeze medium: 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO
Culture conditions: Temperature: 37°C
Atmosphere: air, 95%; carbon dioxide (CO2), 5%
Subculturing instructions: Cell Culture Procedures



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