CF555
General Characteristics
| Age: | <20 years |
| Gender: | Male |
| Disease Origin: | Clival |
| Disease Status: | Recurrent, Metastatic |
| Metastatic Site(s): | Neck, Parotid |
| Sample Origin: | Clivus |
| Source: | Chordoma Foundation/START |
| Notes: | This PDX model is part of a progression model from the same patient; CF555 was derived from a local recurrence of a clival chordoma. Other PDX models in this longitudinal series include CF459 and CF539. Timeline of tumor samples is: CF459 => CF539 => CF555. This PDX model was developed from the same tumor sample as the UM-Chor5C cell line. |
Molecular Features
| Histology: | |
| T localization: | Nuclear |
| P16 expression: | In Progress |
| SMARCB1 expression: | Yes |
| Prior radiation: | Yes |
| Prior systemic therapy: | Yes |
| Chromosomal abnormalities: | In Progress |
| Sequence data: | In Progress |
Growth Characteristics
| Model animal strain: | NSG |