Chordoma Foundation


General Information

Age: <20 years
Gender: Male
Tumor Origin: Clival
Tumor Status: Metastatic (parotid)
Source: Chordoma Foundation/START
Notes: This PDX model is part of a progression model from the same patient; CF539 was derived from a metastatic recurrence (from the parotid) of a clival chordoma.  Other PDX models in this longitudinal series include CF459 (primary tumor) and CF555 (local recurrence).  Timeline of tumor samples is: CF459 => CF539 => CF555.


Molecular Features

T localization: Nuclear
P16 expression:  In Progress
SMARCB1 expression: In Progress
Prior radiation: Yes
Prior systemic therapy: Yes
Chromosomal abnormalities:  In Progress
Sequence data:  In Progress


Growth Characteristics

Model animal strain: NSG





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