Chordoma Foundation

Awarded Grants

The Chordoma Foundation provides ongoing funding to a number of projects identified as major priorities for advancing chordoma research. The Foundation also offers peer-reviewed grants to support investigator-initiated research projects that will accelerate the development of effective treatments for chordoma. These one to two year seed grants are intended to enable investigators to start projects, test hypotheses, or generate preliminary data that could help leverage additional funding sources and lead to sustained chordoma research programs.


Ongoing Strategic Partnerships


Drug Screening Initiative

Gary Gallia, MD, PhD – Johns Hopkins University
Menghang Xia, PhD – NCATS/NIH
>$200,000
over 5 years

The Chordoma Genome Project

Patrick Tarpey, PhD – The Wellcome Trust Sanger Institute
Adrienne Flanagan, MD, PhD – University College London
>$200,000
over 4 years

Genetically Engineered Mouse Model

Michael Kelley, MD
Duke University
> $45,000
over 3 years

2013 Seed Grants


Identifying protein-protein interactions as potential targets for anti-cancer therapy

Jack Greenblatt, PhD
University of Toronto
$25,000

A Targeted Drug Discovery Platform for Chordoma

Cameron Brennan, MD, PhD
Memorial Sloan Kettering
$50,000

Evaluating the Potential of Immune Therapy in Chordoma

Joseph Schwab, MD
Massachusetts General Hospital
$50,000

Development of a Personalized Diagnostic Test for Individuals with Chordoma

Chetan Bettegowda, MD, PhD
Johns Hopkins University
$50,000

A Translational Study of Epigenetic-based Therapy in Chordoma

Gregory Cote, MD, PhD
Massachusetts General Hospital
$50,000

A Mouse Model for Benign Notochordal Tumors

Adrienne Flanagan, MD, PhD
University College London in collaboration with the Jackson Laboratory
$75,000

Developing a Zebrafish Chordoma Model for High-throughput Drug Screening

Andreas Fritz, PhD
Emory University
$25,000

Proteomic Profiling of Chordoma and Normal Notochord

Yasin Temel, MD, PhD
Maastricht University (Netherlands)
$50,000


2011 Seed Grants


Development and Characterization of Chordoma Model Systems from Primary Mouse Notochord Cells

Cheryle Séguin, PhD
University of Western Ontario
$25,000

Evaluation of miRNA-1 as a Potential Therapeutic Target for Treatment of Chordoma

Zhenfeng Duan, MD, PhD
Massachusetts General Hospital
$25,000

Targeting Cancer Initiating Cells with CSPG4-specific mAbs in Chordoma

Soldano Ferrone, MD, PhD
University of Pittsburgh
$25,000

Immunotherapy for Chordoma

Michael Lim, MD
Johns Hopkins University
$25,000

Cancer Stem Cells in Chordoma: Implications for Tumorigenesis and Treatment

Alfredo Quinones-Hinojosa, MD
Johns Hopkins University
$25,000


2008 Seed Grants


A Transgenic Mouse Model of Chordoma

Brian Harfe, PhD
University of Florida
$25,500

Generation of a Chordoma Mouse Model Through Conditional Inactivation of PTEN or TSC1 in the Mouse Notochord

Vijaya Ramesh, PhD
Massachusetts General Hospital
$25,000

Generating Chordoma Cell Lines and Xenografts

Adrienne Flanagan, MD, PhD
UCL Cancer Institute and The Royal National Orthopaedic Hospital, Stanmore
$25,000

Development and Characterization of Chordoma Xenografts

David Loeb, MD, PhD
Johns Hopkins University
$25,000

Molecular Validation of Chordoma Mouse Xenografts

Elena Tamborini, PhD
Istituto Nazionale dei Tumori, Milan
$25,000

Characterization of Chordoma Cell Lines and Tumors

Michael Kelley, MD
Duke University
$45,000